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Gene therapy strategies that activate the Nrf2/ARE pathway in astrocytes have been shown to reduce oxidative stress and provide neuroprotection to DA neurons in both in vitro and in vivo settings (Williamson et al., 2012)

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We examined in particular: Bos taurus ( n =40), Sus scrofa ( n =18), Capra hircus ( n =20), Equus caballus ( n =14), Equus asinus ( n =14) and Ovis aries ( n =15)