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Less extensively discussed factors, whose activity contributes to the hypoxia-inducible factor stabilization, include the decreased activity of the p53, factors modulating the VHLp activity (c-Myc, WSB1), mTOR mediated gamma rays stimulation of stabilization, and changes in calcium homeostasis [21]

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It is important to note that consuming cysteine as part of our usual diet will never exceed the threshold to become toxic