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This analysis considers a variety of factors including the target population (for example, Medicare beneficiaries with select chronic conditions), model eligibility (for example, participant eligibility criteria for inclusion in the model), participant enrollment strategy (for example, mandatory versus voluntary) and, the need to test effects on subgroups

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Samples were centrifuged and serum concentrations of MMA, Hcys, creatinine, vitamin B12, and folate were measured