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Iron deficiency anemia and vitamin B12 deficiency are classic USMLE comparisons because both cause anemia, but the pattern points you to the diagnosis. Iron deficiency causes a microcytic, hypochromic anemia with low

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ROS, which are by-products of aerobic metabolism, are also able to activate these effectors, which in turn can increase proliferation and differentiation both directly or indirectly via ERK1/2 phosphorylation