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Cardiorenal mechanisms of action of glucagon-like-peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors - ScienceDirect

They are inactive and require conversion to the native forms, and are not nearly as effective

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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Grönlund M.M., Gueimonde M., Laitinen K., Kociubinski G., Grönroos T., Salminen S., et al