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Recent advances in EV engineering highlight their potential as precision nanocarriers for miRNA delivery in oncology, underscoring the clinical relevance of EV-mediated miRNA networks in pathological reprogramming [52]

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In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors