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135 Paeoniflorin, the main active metabolite of Paeonia lactiflora Pall., 136 alleviates visceral hypersensitivity and anxiety in irritable bowel syndrome (IBS)-like rats by regulating HPA axis activity and the BDNF/TrkB/phosphorylase Cγ1 (PLCγ1) signaling pathway

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In contrast to submicron particles which are dominated by Brownian motion, this property makes them susceptible to sedimentation in Newtonian liquids