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Currently, the initial test for vitamin B 12 deficiency is to assess serum vitamin B 12 levels, and only when there is low normal vitamin B 12 level, metabolite assay is most often suggested.11 12 However, the consensus for vitamin B 12 threshold levels for ordering the additional tests has not yet been reached

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Although not the focus of this study, an obvious question relates to the identity of the molecular target responsible for the procognitive and synaptogenic activity of dihexa and other AngIV-related compounds