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As two cohorts (the UK Biobank and Mass General Brigham Biobank) reported variants in hg19 coordinates, we avoided having to perform an (error-prone) remapping of variant positions from hg19 to hg38 by filtering to variants present in at least 5 cohorts in the multi-ancestry meta-analyses and at least 3 studies in the European meta-analyses, thereby ensuring that every variant would be present in at least one hg38 study by the pigeonhole principle
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Having megaloblastic anemia can make you more at risk of suffering from osteoporosis, problems with your vision, struggle with memory, worsened cognitive functioning, and if you were to become pregnant, it increases the risk of birth defects in the fetus