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Studying these pivotal changes in the lives of cancer cells—such as their transition from dormancy to active growth—will deepen our scientific understanding of metastasis and, as researchers in the Weinberg Lab hope, lead to more effective treatments for patients with metastatic cancers

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In NSCLC, an increased level of miR-142-5p suppresses PTEN while elevating the levels of PI3K, p-Akt, and PD-L1, thereby facilitating tumor immune escape