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Targeting ferroptosis via iron chelation, enhancing antioxidant defenses, or modulating microglial polarization may represent viable therapeutic approaches

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However, we point commenters to a recent review of PFS intraservice times and times observed in the American College of Surgeons National Surgical Quality Improvement Program (NSQIP), and estimates derived from Medicare anesthesia claims which indicates that NSQIP median operative and anesthesia times are on average, 16 to 17 percent lower than PFS intraservice times