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Parkinson’s Disease - Types, Causes, Symptoms, Risk Factors, Treatment and Prevention PACE Hospitals Parkinson’s Disease definition Parkinson's disease is a slowly progressing brain condition that results in the weakening, degeneration and death of dopaminergic neurons (a type of neuron in the central nervous system that produces dopamine) in the substantia nigra pars compacta (SNpc) which is a part of the brain that controls movement resulting issues with motor skills, such as shaking, rigidity in the arms or legs, or difficulty maintaining balance
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On the other hand, taking into account all the limitations, studying M1-like and M2-like macrophage phenotypes and their overlaps seem to be still useful for our understanding of different immunopathological reactions and diseases and might lead to potential new therapeutical approaches
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