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NNMT sits at high levels in fat tissue, in many cancer cells and in tissue under metabolic stress, where it acts as a metabolic sink: it consumes NAD+, the coenzyme that powers energy… Specifications Dosing information Work out exact pen clicks for any research dose with the Dosage Calculator

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As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)