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Humic substances (HSs) are produced through a specific solvothermal synthesis directed to extract HS from the commercially available compost produced by a Sardinian firm, Verde Vita (s.r.l.), through the oxidative degradation of biomass derived from the organic fraction of urban or agro-industrial waste

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Both drugs have the propensity to cause unwanted urotoxicity, due to the production of acrolein (Brock et al., 1979) (Fig