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OA-VI12 was shown to promote the expression of miR-122-5p while downregulating the expression of MITF and TYR, suggesting that it inhibited melanin synthesis through the miR-122-5p/MITF/TYR axis

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Risk Factors & Individual Sensitivity Higher risk: active acne/eczema, post-procedure skin, stacking multiple exfoliants, very low pH routines