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The redox proteomics analysis of postmortem brains from subjects affected by AD or earlier pathological stages allowed delineation of the involvement of the ox-PTMs of proteins involved in specific cellular functions in the cause-and-effect relationship between increased OS and brain degeneration (5, 6, 299)

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For researchers interested in tissue repair , muscle protein synthesis , or fat metabolism , understanding this IGF-1 pathway becomes essential for setting realistic expectations and designing effective protocols