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10.1091/mbc.12.5.1445 18 BremH.StojadinovicO.DiegelmannR

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Evaluating the structural architecture and spatial conformation of Ipamorelin against classic peptide variants reveals that its strategically engineered intramolecular hydrogen bonding networks and optimized linker regions provide superior spatial complementarity within mammalian target receptor binding pockets, translating directly into heightened functional potency