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Computer-aided identification of potential inhibitors against Necator americanus glutathione S-transferase 3 - PMC

The next day, cells were treated with ferrostatin-1 or TEMPO (Sigma-Aldrich 214000-1 G) or mitoTEMPO for 24 h, followed by RSL3 or ML162 for 48 h in 100 µL cell culture medium

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1 Introduction Diabetic kidney disease (DKD) is one of the most common and severe microvascular complications of diabetes mellitus, representing the leading cause of end-stage renal disease (ESRD) worldwide ( The pathogenesis of DKD is extremely complex, involving dysregulation of multiple metabolic pathways