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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.van Bergenhenegouwen J., Braber S., Loonstra R., Buurman N., Rutten L., Knipping K., Savelkoul P.J., Harthoorn L.F., Jahnsen F.L., Garssen J., et al

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I think you need to be hypervigilant to manage the side effects, getting some ondansetron or ranitidine on board from the get-go to make it more pleasant for the patient