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The critical roles that RTKs and non-RTKs play in promoting carcinogenic signaling pathways in HCC have been brought to light by developments in cancer genetics

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Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of these variations revealed their association with detoxification and antioxidant response such as Glutathione S transferase (e.g., GstD4 , GstD5, GstD6, GstD7, GstD10, GstE1, GstE2, GstE5, GstE6, GstE8, GstE11, GstE14, GstO2, GstT3 ) (Fig