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Mutations in α-Syn cause imbalances in mitochondrial dynamics, particularly Drp1-mediated mitochondrial fission ( It was observed that DJ-1 exerts a regulatory effect on Drp1, thereby facilitating mitochondrial division and protecting neurons from oxidative stress-induced damage (Qin et al., 2017

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Acute reduction of myocardial infarct size by a hydroxymethyl glutaryl coenzyme A ruductase inhibitor is mediated by endothelial nitric oxide synthetase

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