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The phenotype of these patients is distinct from other bone marrow failure syndromes and therefore this disease provides an opportunity to identify new regulatory aspects found in HSCs

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TB-500 follows a loading phase of 2 mg to 2.5 mg twice per week for the first 4 to 6 weeks, followed by a maintenance phase of 2 mg to 2.5 mg once per week for an additional 4 to 6 weeks