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From a functional medicine standpoint: Topical copper peptides are ideal for localized, consistent, preventative skin longevity Injectable copper peptides are reserved for select patients seeking more aggressive or systemic regenerative support For this reason, many patients begin with topical copper peptides and only consider injectable options when clinically appropriate

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For efficacy, FDA found exactly one trial in UC patients, a 53 person rectal enema study that exists only as a conference abstract, with no real detail on inclusion criteria or statistical methods, and no statistically significant benefit over placebo¹