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At the same time, it hinders the permeation of active ingredients that may benefit the skin condition and the health of the whole body [2]

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This was the first clinical study, hinting that brain iron chelation might modify disease progression in AD, although no follow-up clinical studies have been conducted over the past 30 years, potentially due to the constraints of time and funding over the 2-year treatment period (Percy et al., 2011)