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In heterozygous DPYD carriers treated with a standard fluoropyrimidine dose, three studies reported no deaths, 60,65,67 and five studies reported that 14.3% to 100% of carriers died as a result of toxicity

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“Restless Legs Syndrome Is Associated with Mast Cell Activation Syndrome.” Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine, vol