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10.1073/pnas.87.16.6258 [DOI] [PMC free article] [PubMed] [Google Scholar] 34.Hirotsu Y, Katsuoka F, Funayama R, Nagashima T, Nishida Y, Nakayama K, et al

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It is important to recognize that seizures stimulate the production of free radicals and mitochondrial dysfunction, resulting in a chronic redox state, neuronal changes and an increased susceptibility to seizures, leading to epilepsy 42