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The initial phase typically begins with isolating microorganisms from various sources, including the GIT of healthy fish, aquatic environments, and fermented products (Merrifield et al., 2010)

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This hyper ECD motion was propagated to the receptor TMD, with motions within TMs 3 and 7, creating a wider TM pocket that also influences the positioning of the N-terminus of the Cagri peptide (Fig