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Introduction Alzheimer’s disease (AD) is a devastating, progressive neurodegenerative disease known to cause dementia in the elderly [1, 2], contributing to 60–70% of all dementia cases [3, 4] that have affected more than 37 million people across the globe

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These results indicated that FOXO4‐DRI worked on ECM‐receptor interaction pathway in mice to ameliorate BLM‐induce PF