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If you have MTHFR, gluten isn't just a gut problem: it disrupts the very pathway your MTHFR gene depends on. Two things happen simultaneously: → Gut wall damage reduces your capacity to

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It has been shown that neutrophils release elastase and PR3 together with aggNETs, which can then engulf and degrade MSU crystals, thus preventing further activation of the NLRP3 inflammasome and subsequent release of pro-inflammatory cytokines like IL-1β and IL-18 (Figure 3)