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The analysis suggested that when holoTC is 50 pmol/L, deficiency is unlikely

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However, a notable side effect was observed: MT-II-treated normal C57BL/6J mice exhibited significant weight loss, with their average weight decreasing from a baseline of 30.9 ± 1.4 grams to 26.5 ± 1.7 grams after the 14-day treatment course, a change not seen in vehicle-treated controls