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10.1186/S12883-022-02815-X/TABLES/2 [DOI] [PMC free article] [PubMed] [Google Scholar] Lv J, Xu S, Meng C et al (2023) Ferroptosis participated in hippocampal neuroinflammation damage of in offspring rats after maternal sleep deprivation

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"Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism." [1] Clinical protocols typically target sustained telomerase activation over 10-20 day cycles based on transgenic mouse studies where daily 1 mg subcutaneous injections extended average lifespan by 13.5% and maximum lifespan by 13.9% [2]