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Reduced levels of serum motilin and gastrin, together with lower pro-inflammatory cytokines and reduced tissue NF-κB and COX-2 levels, and increased serum somatostatin, vasoactive intestinal peptide, and tissue SOD, NO, and MDA levels were associated with genistein- and daidzein-rich fermented soy (shuidouchi) in an experimental animal model (275)

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Peptides operate through various mechanisms, including by stimulating skin cell proliferation, augmenting collagen synthesis, preventing collagen degradation, activating growth factors, and directly inhibiting facial muscle contraction, resulting in diminished wrinkles and improved skin appearance [3]