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In a study done by Gergely et al [6] , it was found that mitochondria which are the organelles that control the signal processing of T cells are dysfunctional in lupus patients, exhibit a higher-than-normal mitochondrial transmembrane potential (ΔΨm) or mitochondrial hyperpolarization and are ATP (adenosine triphosphate) depleted which predispose to cell death by necrosis instead of apoptosis

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Normally, ubiquinone is efficiently reduced to ubiquinol during absorption or shortly after entering the bloodstream