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mTORC1 inhibition via rapamycin can attenuate pyroptosis by reducing mitochondrial ROS and activating mitophagy, thereby limiting inflammasome activation
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Therefore, maintaining a healthy weight, being physically active, and consuming a balanced diet are effective ways a person can lower his or her risk of developing or dying from cancer (see sidebar on Reduce Your Risk for Cancer by Maintaining a Healthy Weight, Being Physically Active, and Consuming a Balanced Diet)
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