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The optimal concentration for over-the-counter products typically ranges from 0.1% to 2% GHK-Cu, with many studies suggesting 0.5% as an effective sweet spot for benefits without adverse reactions

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Second, we believe that a payment methodology that leverages a prospective performance threshold would limit the magnitude of ASM's negative and positive payment adjustments and, ultimately, the model's incentives to improve performance compared to our proposal to scale the payment adjustments distributed to ASM participants to equal the amount of an ASM incentive pool