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Pre-clinical findings point to activity across multiple pathways: upregulation of vascular endothelial growth factor (VEGF), modulation of nitric oxide synthesis, interaction with growth hormone receptor signaling, and what researchers describe as a cytoprotective effect on epithelial and endothelial tissue

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10.1164/ajrccm.151.5.7735614 [DOI] [PubMed] [Google Scholar] 103.Grandjean EM, Berthet P, Ruffmann R, Leuenberger P