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For this purpose, human Diphtheria Toxin Receptor (DTR, which is not expressed in mice) was overexpressed in Collagen Type I and Lrat expressing activated HSCs, so that administration of Diphtheria Toxin-α (DTA) to CCl 4 -injured mice induced cellular death of DTR + Col1a1 + Lrat + aHSCs
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doi:10.1016/s1521-6918(03)00107-0 ^ National Center for Biotechnology Information
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