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(IV) Although many researchers have devoted themselves to uncovering the precise mechanisms of ferroptosis and have made some achievements, the existing studies mostly focused on the upstream pathways of lipid peroxidation, leaving largely unexplored the downstream molecular pathways or key molecular junctions after the initiation of ferroptosis

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As presented in the figure, NPs demonstrate significant benefits in equine health: They improve sperm quality (enhancing motility and membrane integrity while reducing abnormalities), accelerate wound healing and infection resolution and modulate immune responses by stimulating IL‐10 production in lung lymphocytes, leading to better respiratory function