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Kupffer cells are highly phagocytic and contain elevated levels of enzymes like glucose 6-phosphate dehydrogenase and peroxidase, enhancing their capacity to clear pathogens [27] Stellate cells, located in the space of Disse, are the primary storage site for vitamin A, storing retinol and retinyl palmitate within cytoplasmic lipid droplets[28]

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PCSK9: a convertase that coordinates LDL catabolism