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However, risk of congenital anomalies may be related to both timing of the change (with higher risk when the switch to PTU is not made until late in the first trimester) and to the MMI dose employed (with both higher MMI doses and longer duration of exposure associated with risk of anomalies in the Korean study) (463-465)

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Side effects of shoulder cortisone injections The most common side effects of a shoulder steroid injection include [1-2]: Pain, swelling, or bruising in the injection site