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It is commonly said that in abnormal conditions, the balance of pro-angiogenic and anti-angiogenic factors is reversed in comparison with normal conditions, so that the strength of pro-angiogenics increases and consequently not only leads to the proliferation of endothelial cells but also the shape and permeability of newly formed vessels and even in some cases the pattern of blood flow in them will be different from normal counterparts

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Response: We note that an alternative to our proposal to value the new CPT codes would be to establish G-codes to maintain the pre-existing coding and valuation