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Time-resolved sampling during and immediately after exercise, combined with targeted metabolomic profiling of short-chain fatty acids, bile acids, and tryptophan-derived metabolites, may help separate fast neurogenic regulation from slower microbiota-driven adaptations 111,112,113

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717,718 Queuosine (Q) is a hypermodified, 7-deazaguanosine incorporated into the 34th or “wobble” position of the anticodon loop of four specific tRNAs (Asn, Asp, Tyr and His) that decode synonymous NA C and NA U (N = A, U, C or G) codons