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In the present study, we provide the novel evidence that Gstp −/− mice showed both the notable higher mortality rate and serum HMGB1 level, as well as severer septic pulmonary injury compared with wild-type mice after CLP surgery

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pGEX6P-1-RGG3 was constructed by PCR using pGEX6P-1-EWS as a template and contained amino acids 545–656 of EWS cloned into pGEX6P-1 using RGG3 forward and reverse primers