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While preclinical evidence strongly supports this mechanistic convergence, human validation remains limited—largely confined to biomarker studies of sulforaphane—highlighting the need for cautious, stepwise clinical translation

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The mitochondria-targeted antioxidant MitoQ ameliorates inorganic arsenic-induced DCs/Th1/Th2/Th17/Treg differentiation partially by activating PINK1-mediated mitophagy in murine liver