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MK677 is highly potent and more selective than GHRP6, meaning it produces fewer negative side effects and may be better tolerated

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This is relevant, as thiazides in general have been proposed to promote metabolic dysregulation by inhibiting insulin secretory responses to nutrients through their hypokalemic effects (Zillich et al., 2006), and perhaps by direct effects on renal gluconeogenesis (Fulgraff et al., 1972)