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At present, given lack of definitively proven efficacy, together with high costs and potential side effects, eculizumab is not recommended for the treatment of GBS, and large, randomised controlled trials are needed to establish its potential clinical utility
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Like in the reduction of nitrile to aldehydes, the second hydride addition does not occur, and the hydrolysis of the boronic ester intermediate gives the corresponding aldehyde as the final product
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