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The strongest gene expression changes include upregulation of S-assimilation pathway genes SULTR1;1 Os03g0195800, SULTR4;1 Os09g0240500, ATPS 0s03g0743900, APRL1 Os07g0509800, SAT Os05g0533500, and OASTL Os12g0625000
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For example, mitochondrial dysfunction is prevalent in both idiopathic ASD (31) and is associated with Rett syndrome (32–34), PTEN mutations (35), Phelan-McDermid syndrome (36), 15q11-q13 duplication syndrome (37, 38), Angelman syndrome (39), Septo-optic dysplasia (40), and Down syndrome (41, 42)