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Prostate cancer induces changes in neutrophil glutathione metabolism. A... | Download Scientific Diagram

doi: 10.1016/j.yexcr.2016.11.008, 57 HeC

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It is therefore not surprising that, based on the premise that the cumulative effect of subtle variations in key genes or regulatory pathways contributes to disease vulnerability ( It is important to clarify that, whereas population-level PRS models require formal effect-size modeling, linkage disequilibrium correction, ancestry calibration, and validation across large cohorts, the score used in this workflow is a functional polygenic score (PRS-F) designed for mechanistic, individual-level interpretation rather than for epidemiological prediction