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Lipids required for ATG8 lipidation and membrane extension are delivered to the phagophore via ATG2 and ATG9, where ATG9 acts as a seed to initiate lipid transfer by ATG2 that acts as a hose funneling lipids from relevant compartments (e.g., the ER) to the phagophore (52–54, 76–78) ( Figure 1 , panel 3)

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Genotoxicity in bacterial cells substantially decreased compared to 3R4F Note: these data alone do not imply or represent a claim of reduced exposure or reduced risk