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Supplementation should be used with caution in cats as certain compounds that appear safe for dogs and humans may be toxic or potentiate toxic reactions (for example, lipoic acid 6 )

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Membranes were blocked with 4% non-fat milk in 1× PBS for 45 min at ambient temperature, then incubated with a 1:5,000 dilution of rabbit anti-Tle polyclonal antisera 12 in 1× PBS, 4% non-fat milk overnight